Nomifensine

Estazolam: Estazolam , muag nyob rau hauv cov npe nrov Prosom ntawm lwm tus, yog kev siv tshuaj tawm ntawm lub cev triazolobenzodiazepine (TBZD), uas yog benzodiazepines (BZDs) fused nrog lub nplhaib triazole. Nws muaj cov tshuaj anxiolytic, anticonvulsant, hypnotic, sedative thiab cov leeg pob txha zoo nkauj. Estazolam yog qhov ncauj nruab nrab-benzodiazepine. Nws siv rau luv kho mob insomnia.
Triazolam: Triazolam , muag nyob hauv hom npe lag luam Halcion ntawm lwm tus, yog lub hauv nruab nrab hlab hlwb (CNS) depressant tranquilizer ntawm triazolobenzodiazepine (TBZD) chav kawm, uas yog benzodiazepine (BZD) derivatives. Nws muaj cov tshuaj pharmacological zoo ib yam li lwm cov benzodiazepines, tab sis nws feem ntau tsuas yog siv los ua ib qho tshuaj loog kom kho qhov tsis txaus ntseeg. Ntxiv nrog rau cov khoom siv hypnotic, triazolam amnesic, anxiolytic, sedative, anticonvulsant, thiab cov leeg ua kom lub zog ua haujlwm yog cov lus hais, Vim tias nws luv luv ib nrab-lub neej, triazolam tsis ua haujlwm rau cov neeg mob uas tau paub ntau dhau caij los yog sawv ntxov.
Lormetazepam: Lormetazepam , muag nyob rau hauv hom tshuaj npe Noctamid ntawm lwm tus, yog cov tshuaj uas yog ib qho luv luv mus rau nruab nrab ua yeeb yam 3-hydroxy benzodiazepine derivative thiab temazepam analogue. Nws muaj hypnotic, anxiolytic, anticonvulsant, sedative, thiab cov leeg pob txha zoo nkauj.
Temazepam: Temazepam , muag nyob rau hauv cov npe nrov Restoril ntawm lwm tus, yog cov tshuaj siv los kho insomnia. Siv li no feem ntau yuav yog tsawg dua kaum hnub. Nws yog noj ntawm qhov ncauj. Cov nyhuv feem ntau pib hauv ib teev thiab kav ntev txog li yim teev.
Midazolam: Midazolam , muag nyob hauv hom npe nrov Versed , ntawm lwm tus, yog cov tshuaj benzodiazepine siv rau cov tshuaj loog, txheej txheem loog, teeb meem tsaug zog, thiab ntxhov siab hnyav. Nws ua haujlwm los ntawm kev ntxias lub sijhawm pw tsaug zog, txo kev ntxhov siab, thiab ua rau lub peev xwm tsis muaj peev xwm tsim kev nco tshiab. Nws kuj tseem muaj txiaj ntsig rau kev kho mob chua leeg. Midazolam tuaj yeem muab los ntawm qhov ncauj, ua pa, lossis txhaj tshuaj rau hauv cov leeg, los ntawm kev txau rau hauv lub qhov ntswg, lossis ntawm sab plhu. Thaum muab tshuaj rau hauv, nws feem ntau pib ua haujlwm li ntawm tsib feeb; thaum txhaj rau hauv cov leeg, nws tuaj yeem siv sijhawm kaum tsib feeb los pib ua haujlwm. Cov nyhuv no nyob ntev li ntawm ib thiab rau teev.
Brotizolam: Brotizolam yog ib qho tshuaj sedative-hypnotic thienotriazolodiazepine uas yog benzodiazepine analog. Nws muaj cov tshuaj anxiolytic, anticonvulsant, hypnotic, sedative thiab cov leeg pob txha zoo nkauj, thiab tau txiav txim siab zoo ib yam li lwm qhov kev ua yeeb yam luv luv hypnotic benzodiazepines xws li triazolam lossis midazolam. Nws yog siv nyob rau hauv kev kho mob luv luv ntawm kev hnyav insomnia. Brotizolam yog qhov muaj zog tshaj plaws thiab kev ua yeeb yam luv luv hypnotic, nrog cov koob tshuaj txij li 0.125 txog 0.25 milligrams, uas tshem tawm sai sai nrog qhov nruab nrab ib nrab-lub neej ntawm 4.4 teev.
Quazepam: Quazepam yog lub sijhawm ntev coj los ua benzodiazepine derivative tshuaj tsim los ntawm Schering Corporation hauv xyoo 1970. Quazepam yog qhia rau kev kho mob tsis tsaug zog suav nrog kev suav nrog kev pw tsaug zog thiab kev saib xyuas kev pw tsaug zog. Quazepam tsim kev tsis zoo ntawm lub cev muaj zog thiab muaj qhov xaiv hypnotic thiab anticonvulsant muaj zog nrog qhov muaj feem tsawg tshaj li qhov muaj peev xwm tshaj li lwm cov benzodiazepines. Quazepam yog qhov ua tau zoo hypnotic uas tsim thiab tswj kev pw tsaug zog yam tsis muaj kev cuam tshuam ntawm lub tsev pw tsaug zog.
Loprazolam: Loprazolam ( triazulenone ) ua lag luam nyob hauv ntau lub npe muaj npe yog cov tshuaj benzodiazepine. Nws muaj cov tshuaj anxiolytic, anticonvulsant, hypnotic, sedative thiab cov leeg pob txha zoo nkauj. Nws yog ntawv tso cai thiab kev lag luam rau lub sij hawm luv luv ntawm kev kho mob tsis xwm yeem-mob hnyav.
Doxefazepam: Doxefazepam yog tshuaj kho mob benzodiazepine Nws muaj cov tshuaj anxiolytic, anticonvulsant, sedative thiab cov leeg pob txha zoo nkauj. Nws yog siv kho raws li qhov hypnotic. Raws li Babbini thiab cov npoj yaig hauv xyoo 1975, qhov keeb kwm ntawm flurazepam no yog nruab nrab ntawm 2 thiab 4 npaug tshaj li muaj zog tshaj tom kawg thaum tib lub sijhawm ua ib nrab li muaj tshuaj lom hauv cov tsiaj kuaj.
Cinolazepam: Cinolazepam yog ib qho tshuaj uas yog benzodiazepine derivative. Nws muaj anxiolytic, anticonvulsant, sedative thiab cov leeg pob txha relaxant zog.nqa rau nws cov khoom muaj zog sedative, nws yog siv feem ntau ua hypnotic.
Climazolam: Climazolam ( Ro21-3982 ) tau nkag rau hauv daim ntawv tso cai raws li kev kho tsiaj txhu tshuaj lag luam los ntawm Swiss Pharmaceutical tuam txhab Gr underub raws li kab mob ua haujlwm Climasol . Climazolam yog benzodiazepine, tshwj xeeb yog ib qho imidazobenzodiazepine derivative tsim los ntawm Hoffman-LaRoche. Nws yog qhov zoo sib xws hauv cov qauv rau midazolam thiab diclazepam thiab yog siv rau hauv cov tsiaj kho kom zoo rau cov tsiaj tsis nco qab.
ATC code N05: ATC code N05 Psycholeptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm cov cim alphanumeric tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N05 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
Glutethimide: Glutethimide yog hypnotic sedative uas tau qhia los ntawm Ciba hauv 1954 ua lwm txoj hauv kev nyab xeeb rau barbiturates kho insomnia. Ua ntej tsis ntev, txawm li cas los xij, nws tau pom tseeb tias glutethimide tsuas yog ua kom muaj kev quav tshuaj thiab ua rau cov tsos mob tshem tawm zoo sib xws. Doriden yog lub hom npe-version. Cov qib tam sim no hauv Tebchaws Asmeskas taw tes rau nws qhov nws tsuas yog siv rau kev tshawb fawb me me. Kev tsim cov tshuaj no tau txiav tawm hauv Asmeskas hauv xyoo 1993 thiab tau nres hauv ntau lub tebchaws sab hnub tuaj European xyoo 2006.
Methyprylon: Methyprylon (Noludar) yog ib lub zog ntawm piperidinedione derivative tsev neeg tsim los ntawm Hoffmann-La Roche.n cov tshuaj no tau siv rau kev kho mob tsis tuaj yeem, tab sis tam sim no tsis tshua muaj siv vim nws tau hloov los ntawm cov tshuaj tshiab dua nrog kev phiv tsawg dua, xws li benzodiazepines.Methyprylon tau raug tshem tawm ntawm Asmeskas kev ua lag luam thaum lub Rau Hli 1975 thiab Canadian kev ua lag luam nyob rau lub Cuaj Hli 1990. \ n Muaj qee lub npe lag luam yog Noctan thiab Dimerin.
Pyrithyldione: Pyrithyldione yog lub tshuaj psychoactive invented nyob rau hauv 1949.nAn kev txhim kho txoj kev tsim khoom tau raug xaj los ntawm Roche xyoo 1959. Nws tau siv los ua lub siab tsis zoo los yog ua kom loog thiab kwv yees muaj tshuaj tsawg dua barbiturates. Niaj hnub no, cov khoom siv no tsis siv lawm. Qee zaum Agranulocytosis tau tshaj tawm tias yog vim muaj kev cuam tshuam tsis zoo. Pyrithyldione kuj tseem yog CYP2D6 tsim kom zoo nkauj tab sis tsis muaj zog npaum li glutethimide Hauv kev tshawb fawb, nws nce O-Demethylation ntawm codeine los ntawm 20%.
ATC code N05: ATC code N05 Psycholeptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm cov cim alphanumeric tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N05 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
Zopiclone: Zopiclone , muag nyob rau hauv hom npe Imovane ntawm lwm tus, yog nonbenzodiazepine siv los kho kev nyuaj pw. Zopiclone yog cov molecularly sib txawv ntawm cov tshuaj benzodiazepine thiab tau faib ua ib hom cyclopyrrolone. Txawm li cas los xij, zopiclone tsub kom lub cev sib luag ntawm cov neurotransmitter gamma-aminobutyric acid (GABA) nyob rau hauv nruab nrab cov hlab hlwb, los ntawm kev hloov kho benzodiazepine receptors tib txoj kev uas cov tshuaj benzodiazepine ua.
Zolpidem: Zolpidem , muag hauv cov lag luam muaj npe Ambien , ntawm lwm tus, yog cov tshuaj siv feem ntau siv rau kev kho mob luv luv ntawm cov teeb meem pw tsaug zog. Cov lus qhia pom zoo tias nws tsuas yog siv tom qab kev paub txog kev coj tus cwj pwm kom tsis tsaug zog thiab hloov cwj pwm, xws li kev pw tsaug zog, tau sim lawm. Nws txo qis lub sijhawm kom pw tsaug zog pib li ntawm kaum tsib feeb thiab kom txhaj ntau dua pab cov neeg tsaug zog ntev dua. Nws yog noj ntawm qhov ncauj thiab muaj nyob hauv cov ntsiav tshuaj zoo, sublingual ntsiav tshuaj, lossis tshuaj tsuag qhov ncauj.
Zaleplon: Zaleplon , muag nyob rau hauv hom tshuaj npe Sonata ntawm lwm tus, yog ib qho sedative-hypnotic, siv los kho insomnia. Nws yog hom nonbenzodiazepine hypnotic los ntawm chav kawm pyrazolopyrimidine.
Eszopiclone: Eszopiclone , muag nyob rau hauv hom lag luam lub npe Lunesta ntawm lwm tus, yog ib hom tshuaj siv hauv kev kho mob ntawm insomnia. Pov thawj txhawb me ntsis mus rau cov txiaj ntsig mus txog rau rau lub hlis. Nws yog noj ntawm ncauj.
ATC code N05: ATC code N05 Psycholeptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm cov cim alphanumeric tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N05 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
Melatonin: Melatonin yog ib yam tshuaj uas tso tawm los ntawm lub caj pas pineal thaum hmo ntuj, thiab tau ntev ua rau muaj kev cuam tshuam nrog lub sijhawm tswj kev pw tsaug zog. Raws li kev noj zaub mov zoo, nws feem ntau siv rau kev kho mob ncua sij hawm ntev, xws li los ntawm dav hlau lag luam lossis hloov chaw ua haujlwm, thiab feem ntau noj ntawm qhov ncauj. Cov pov thawj ntawm nws cov txiaj ntsig rau qhov kev siv no, txawm li cas los xij, tsis muaj zog. Kev tshuaj xyuas 2017 pom tias pib pw tsaug zog tshwm sim rau 6 feeb sai dua nrog kev siv, tab sis pom tsis muaj kev hloov hauv lub sijhawm tag nrho kev pw tsaug zog. Cov melatonin receptor agonist tshuaj ramelteon yuav ua haujlwm ntxiv rau cov tshuaj melatonin, ntawm tus nqi ntau dua tab sis nrog cov kev tsis zoo, rau qee qhov mob pw tsaug zog.
Ramelteon: Ramelteon , muag nyob hauv hom npe nrov npe Rozerem ntawm lwm tus, yog kev noj tshuaj pw tsaug zog uas xaiv khi rau MT 1 thiab MT 2 receptors hauv suprachiasmatic nucleus (SCN), es tsis txhob khi rau GABA A receptors, xws li nrog cov tshuaj zoo li zolpidem.
ATC code N05: ATC code N05 Psycholeptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm cov cim alphanumeric tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N05 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
Methaqualone: Methaqualone yog ib qho tshuaj ua kom loog thiab hypnotic. Nws tau muag hauv cov npe lag luam Quaalude thiab Sopor ntawm lwm tus, uas muaj cov tshuaj methaqualone 300 mg, thiab muag ua cov tshuaj sib xyaw ua ke nyob rau hauv hom tshuaj npe Mandrax uas muaj 250 mg methaqualone thiab 25 mg diphenhydramine nyob rau tib lub ntsiav tshuaj, feem ntau nyob hauv Europe. Kev tsim tawm ntawm cov tshuaj methaqualone tau raug tso tseg ib nrab nyob rau xyoo 1980 vim muaj kev tsim txom ntau thiab ua rau muaj yees ntxiv. Nws yog tus tswv cuab ntawm chav kawm quinazolinone.
Clomethiazole: Clomethiazole yog kev ua kom loog thiab hypnotic tsim los ntawm Hoffmann-La Roche xyoo 1930. Cov tshuaj yeeb yaj kiab yog siv hauv kev kho mob thiab tiv thaiv cov tsos mob ntawm tus mob cawv haus cawv.
Bromisoval: Bromisoval (INN), feem ntau hu ua bromovalerylurea , yog hypnotic thiab sedative ntawm pawg bromoureide nrhiav tau los ntawm Knoll xyoo 1907 thiab muaj ntawv sau txog xyoo 1909. Nws tau ua lag luam dhau lub txee hauv Asia hauv ntau cov npe kev lag luam, feem ntau yog ua ke nrog nonsteroidal anti-inflammatory. tshuaj.
Carbromal: Carbromal yog qhov hypnotic / sedative Ameslikas synthesized hauv 1909 los ntawm Bayer thiab tom qab ntawd ua lag luam li Adalin . Cov tshuaj tom qab muag los ntawm Parke-Davis hauv kev sib xyaw nrog pentobarbital, hauv qab lub npe Carbrital .
Scopolamine: Scopolamine , tseem hu ua hyoscine , lossis Ntxwg Nyoog cov pa , yog lub ntuj lossis synthetically tsim tropane alkaloid thiab tshuaj anticholinergic uas tau siv los ua tshuaj rau kev kho mob ua kom muaj mob thiab kev xav tom qab thiab ntuav thiab ntuav. Nws kuj tseem siv qee zaum ua ntej kev phais mob kom txo tau cov qaub ncaug. Thaum siv los ntawm kev txhaj tshuaj, cov teebmeem pib tom qab txog 20 feeb thiab kav ntev txog li 8 teev. Nws kuj tseem siv tau los siv ntawm ncauj thiab ua rau kis transdermal. Nws muaj nyob hauv Ntiaj Teb Kev Noj Qab Haus Huv Lub Npe rau Cov Tshuaj Tseem Ceeb.
Propiomazine: Propiomazine yog ib qho tshuaj antihistamine thaiv H1 receptors. Nws yog siv los kho kev tsis txaus ntseeg, thiab ua rau tsaug zog lossis tsaug zog thiab daws kev ntxhov siab ua ntej lossis thaum phais lossis lwm cov txheej txheem thiab ua ke nrog analgesics tseem thaum ua haujlwm. Propiomazine yog phenothiazine, tab sis tsis yog siv los ua neuroleptic vim tias nws tsis thaiv dopamine receptors zoo.
Triclofos: Triclofos yog ib qho tshuaj sedative uas siv tsis tshua siv los kho insomnia.
Ethchlorvynol: Ethchlorvynol yog GABA-ergic sedative thiab hypnotic / soporific tshuaj tsim los ntawm Pfizer hauv xyoo 1950. Hauv Tebchaws Asmeskas nws tau muag los ntawm Abbott Lub chaw soj nstuam hauv qab kev lag luam npe Placidyl . Placidyl muaj nyob rau hauv 200 mg, 500 mg, thiab 750 mg lub zog gel puv tsiav tshuaj. Thaum 500 mg thiab 750 mg zog tsiav tshuaj tau siv rau kev txo kev tsaug zog ntawm kev tsaug zog, qhov 200 mg zog tsiav tshuaj tau xav kom siv los rov ua kom pw tsaug zog thaum sawv ntxov. Abbott tsis tu ncua ntau lawm hauv xyoo 1999, vim nws tau hloov los ntawm benzodiazepine tsev neeg thiab nws txoj kev tsim txom ntau, tom qab ntawd Placidyl muaj li ib xyoos hauv Tebchaws Asmeskas. Txawm hais tias, raws li kev xav, ethchlorvynol tuaj yeem tsim cov khoom lag luam muag hauv Tebchaws Meskas los ntawm lwm lub tuam txhab kws kho mob, tsis muaj ib lub tuam txhab tshuaj ua haujlwm tau xaiv. Cov neeg uas muaj daim ntawv xaj yuav raug cai rau kev thauj khoom tuaj yeem thauj tus nqi ntawm ethclorvynol nrog lawv mus rau Tebchaws Meskas.
Valerian (herb): Valerian yog lub hnub qub kev cog paj uas ib txwm muaj nyob rau Europe thiab Asia. Nyob rau lub caij ntuj sov thaum lub chaw ua haujlwm cov laus yuav muaj qhov siab txog 1.5 metres (5 ft), nws Dais paj huab zoo nkauj lossis paj dawb uas nyiam ntau hom kab, tshwj xeeb tshaj yog hoverflies ntawm lub genus Eristalis . Nws noj yog khoom noj los ntawm cov kab menyuam ntawm qee hom Lepidoptera, suav nrog lub gug gug.
Hexapropymate: Hexapropymate yog qhov hypnotic / sedative. Nws muaj cov teebmeem zoo ib yam li cov barbiturates thiab tau siv nyob rau xyoo 1970-1980s hauv kev kho insomnia ua ntej yuav hloov nrog cov tshuaj tshiab dua nrog kev txhim kho kev nyab xeeb.
Bromide: Ib qho bromide ion yog qhov tsis zoo raug foob ( Br - ) ntawm lub keeb bromine, ib tus tswv cuab ntawm halogens pawg ntawm lub rooj ntu.
Apronal: Aponal , lossis apronalide , tseem hu ua allylisopropylacetylurea lossis allylisopropylacetylcarbamide , yog qhov tshuaj tiv thaiv hypnotic / sedative ntawm cov ureide (acylurea) pawg tsim tawm xyoo 1926 los ntawm Hoffmann-La Roche uas tsis siv lawm tshwj tsis yog nyob rau hauv Nyijpooj. Txawm hais tias nws tsis yog barbiturate, apronalide yog qhov zoo sib xws hauv cov qauv rau cov barbiturates. Raws li txoj cai, nws zoo ib yam hauv kev nqis tes nrog barbiturates, txawm hais tias muaj kev cuam tshuam me me hauv kev sib piv. Raws li qhov kev tshawb pom tias nws ua rau cov neeg mob tsim muaj thrombocytopenic purpura, apronalide raug rho tawm ntawm kev siv tshuaj.
Valnoctamide: Valnoctamide tau siv nyob rau hauv Fabkis ua sedative-hypnotic txij li xyoo 1964. Nws yog tus txheej txheem isomer ntawm valpromide, valproic acid prodrug; tsis zoo li valpromide, txawm li cas los, valnoctamide yog tsis hloov mus rau hauv nws cov homologous acid, valnoctic acid, nyob rau hauv vivo.
Methylpentynol: Methylpentynol yog ib tug tertiary hexanol nrog hypnotic / sedative thiab anticonvulsant teebmeem thiab ib tug kws uas tsis muaj tshuaj index. Nws twb nrhiav tau los ntawm Bayer nyob rau hauv 1913 thiab siv tsocai tom qab ntawd rau cov kev kho mob ntawm insomnia, tab sis nws siv tau sai sai phased tawm nyob rau hauv cov lus teb rau newer tshuaj nrog deb ntau paaj kev nyab xeeb profiles.
Niaprazine: Niaprazine (INN) yog ib qho tshuaj sedative-hypnotic ntawm pab pawg phenylpiperazine. Nws tau siv rau hauv kev kho mob pw tsaug zog txij thaum ntxov xyoo 1970s hauv ntau lub tebchaws nyob sab Europe suav nrog Fabkis, Ltalis, thiab Luxembourg. Nws nquag siv nrog menyuam yaus thiab tub ntxhais hluas ntawm tus account ntawm nws qhov kev nyab xeeb muaj txiaj ntsig zoo thiab tiv taus cov ntaub ntawv thiab tsis muaj kev tsim txom.
Dexmedetomidine: Dexmedetomidine , muag nyob rau hauv cov npe lag luam Precedex ntawm lwm tus, yog ib qho tshuaj lom neeg mob anxiolytic, ua kom loog, thiab mob tshuaj mob. Dexmedetomidine yog notable rau nws muaj peev xwm mus muab tshuaj kom tsaug zog tsis muaj kev pheej hmoo ntawm kev ua pa nyuaj siab thiab muaj peev xwm muab kev koom tes los yog semi-rousable tshuaj kom tsaug zog.
Detomidine: Detomidine yog ib qho imidazole derivative thiab α 2 -adrenergic agonist, siv los ua tsiaj loj sedative, feem ntau siv hauv nees. Nws feem ntau muaj raws li cov ntsev detomidine hydrochloride. Nws yog cov tshuaj kho mob muaj rau kws kho tsiaj tso rau hauv kev lag luam npe Dormosedan.
Medetomidine: Medetomidine yog cov tshuaj siv hluavtaws siv los ua ob qho kev phais mob ua ntej thiab ua kom loog. Nws feem ntau yog siv los ua cov ntsev hydrochloride, medetomidine hydrochloride, ib qho khoom uas muaj crystalline dawb. Nws yog α2 adrenergic agonist uas tuaj yeem raug tswj hwm raws li cov tshuaj ua kua dej nrog cov dej tsis huv.
Xylazine: Xylazine yog qhov ntsuas ntawm clonidine thiab agonist ntawm α 2 chav kawm ntawm adrenergic receptor. Nws yog siv rau kev ua kom loog, ua kom loog, mob ib ce, thiab ua kom loog hauv tsiaj xws li nees, nyuj thiab lwm yam tsiaj uas tsis yog neeg. Cov kws kho tsiaj kuj siv xylazine li ib tug emetic, tshwj xeeb tshaj yog nyob rau hauv miv.
Romifidine: Romifidine yog ib cov tshuaj uas siv hauv cov tsiaj kho tsiaj yog cov tshuaj sedative nyob hauv cov tsiaj loj xws li nees, txawm hais tias nws yuav siv ntau hom tsiaj. Nws tsis yog siv rau hauv tib neeg, tab sis muaj kev sib txuam zoo hauv cov qauv rau feem ntau siv tshuaj yeeb tshuaj clonidine.
Metomidate: Metomidate yog qhov tsis yog-barbiturate imidazole uas tau tshawb pom los ntawm Janssen Pharmaceutica nyob rau xyoo 1965 thiab hauv cov npe yog muag raws li cov tshuaj sedative-hypnotic siv nyob hauv Europe los kho tib neeg thiab rau kev tawm tsam.
ATC code N05: ATC code N05 Psycholeptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm cov cim alphanumeric tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N05 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
ATC code N06: ATC code N06 Psychoanaleptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm alphanumeric code tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N06 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
ATC code N06: ATC code N06 Psychoanaleptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm alphanumeric code tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N06 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
ATC code N06: ATC code N06 Psychoanaleptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm alphanumeric code tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N06 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
Desipramine: Desipramine , muag nyob rau hauv hom lag luam npe Norpramin ntawm lwm tus, yog tricyclic antidepressant (TCA) siv rau hauv kev kho mob ntawm kev nyuaj siab. Nws ua raws li kev xaiv tus mob norepinephrine reuptake inhibitor, txawm hais tias nws tseem muaj lwm cov haujlwm xws li tsis muaj zog serotonin reuptake inhibitory, α 1- thaiv , antihistamine, thiab anticholinergic cuam tshuam. Cov tshuaj tsis pom tias yog thawj txoj kev kho rau kev nyuaj siab txij li kev qhia txog kev xaiv serotonin reuptake inhibitor (SSRI) cov tshuaj tiv thaiv kab mob, uas muaj cov kev mob tshwm sim tsawg dua thiab muaj kev nyab xeeb nyob rau hauv kev siv ntau dhau.
Imipramine: Imipramine , muag nyob rau hauv hom tshuaj npe Tofranil , ntawm lwm tus, yog tricyclic antidepressant (TCA) feem ntau yog siv hauv kev kho mob ntawm kev nyuaj siab. Nws tseem yog siv los kho kev ntxhov siab vim thiab panic teeb meem. Cov tshuaj no kuj siv rau kho bedwetting. Imipramine noj ntawm qhov ncauj.
Imipraminoxide: Imipraminoxide , lossis Imipramine N -oxide , yog tricyclic antidepressant (TCA) uas tau nkag mus rau hauv Tebchaws Europe xyoo 1960 rau kev kho mob ntawm kev nyuaj siab.
Clomipramine: Clomipramine , muag nyob rau hauv hom tshuaj npe Anafranil ntawm lwm tus, yog tricyclic antidepressant (TCA). Nws yog siv rau kev kho mob ntawm obsessive – compulsive tsis meej, ceeb ntshai tsis meej, loj depressive tsis meej, thiab mob mob. Nws yuav nce txoj kev pheej hmoo tua tus kheej hauv cov hnub nyoog qis dua 25. Nws noj los ntawm qhov ncauj. Nws kuj tau siv los kho kev ntxov ntxov.
Opipramol: Opipramol , muag nyob hauv hom npe nrov npe Insidon ntawm lwm tus, yog ib qho kev txhawj xeeb thiab tshuaj tua kab mob uas siv thoob plaws hauv Europe. Txawm hais tias kev siv tshuaj tricyclic dibenzazepine (iminostilbene) derivative zoo ib yam li imipramine, opipramol tsis yog monoamine reuptake inhibitor zoo li feem ntau lwm yam tricyclic antidepressants, thiab hloov, tsis txawv ntawm cov tshuaj tiv thaiv kab mob, ua feem ntau ua rau sigma receptor agonist. Nws tau tsim los ntawm Schindler thiab Blattner hauv xyoo 1961.
Trimipramine: Trimipramine , muag nyob rau hauv cov npe lag luam Surmontil ntawm lwm tus, yog tricyclic antidepressant (TCA) uas yog siv los kho kev nyuaj siab. Nws kuj tau muab siv rau nws sedative, anxiolytic, thiab tsis muaj zog antipsychotic los nyob rau hauv cov kev kho mob ntawm insomnia, ntxhov siab vim kev ntshawv siab, thiab psychosis, ntsig txog. Cov tshuaj tau piav qhia yog atypical lossis "thib ob tiam \" TCA vim tias, tsis zoo li lwm yam TCAs, nws zoo li yog qhov tsis muaj zog monoamine reuptake inhibitor. Ib yam li ntawd rau lwm tus TCAs Txawm li cas los, trimipramine tsis muaj antihistamine, antiserotonergic, antiadrenergic, antidopaminergic, thiab anticholinergic kev ua ub no.
Lofepramine: Lofepramine , muag nyob hauv cov npe lag luam Gamanil , Lomont , thiab Tymelyt ntawm lwm tus, yog tricyclic antidepressant (TCA) uas yog siv los kho kev nyuaj siab. Lub TCAs yog li lub npe raws li lawv qhia cov khoom teejtug uas yog muaj peb ib ncig nyob rau hauv lawv cov tshuaj qauv. Zoo li feem ntau TCAs lofepramine yog ntseeg mus ua hauj lwm nyob rau hauv relieving kev nyuaj siab los ntawm kev ua ntsees ntawm lub neurotransmitters norepinephrine thiab serotonin nyob rau hauv lub synapse, los ntawm inhibiting lawv reuptake. Nws feem ntau suav tias yog TCA thib peb, zoo li tsis zoo li TCA thawj- thiab tiam thib ob nws muaj kev nyab xeeb rau kev haus ntau dhau thiab muaj cov kev mob tshwm sim me me thiab tsawg dua.
Dibenzepin: Dibenzepin , muag hauv qab hom npe Noveril ntawm lwm tus, yog tricyclic antidepressant (TCA) siv dav thoob plaws hauv Tebchaws Europe rau kev kho mob ntawm kev nyuaj siab. Nws muaj cov txiaj ntsig zoo sib xws thiab muaj kev cuam tshuam ntawm lwm qhov TCA zoo li imipramine tab sis muaj cov kev mob tshwm sim tsawg dua.
Amitriptyline: Amitriptyline , muag nyob rau hauv lub npe lag luam Elavil ntawm lwm tus, yog tricyclic antidepressant feem ntau siv los kho kev mob ntshav siab thiab ntau yam mob ntsws mob los ntawm mob neuropathic rau fibromyalgia rau mob taub hau thiab mob taub hau. Vim qhov ntau zaus thiab qhov tshwm sim ntawm cov kev mob tshwm sim, amitriptyline feem ntau pom tias yog kev kho nsecond-kab rau cov cim no.
Nortriptyline: Nortriptyline , muag nyob hauv cov npe lag luam Pamelor, ntawm lwm tus, yog cov tshuaj siv los kho kev nyuaj siab, mob neuropathic, mob siab hyperactivity tsis meej (ADHD), haus luam yeeb tsis ua thiab ntxhov siab. Raws li nrog rau ntau yam antidepressants, nws siv rau cov neeg hluas uas muaj kev nyuaj siab thiab lwm yam mob hlwb kev ntshawv siab tej zaum yuav muaj vim nce suicidality nyob rau hauv lub 18-24 pejxeem pib kho mob. Nortriptyline yog qhov kev kho mob tsis tshua nyiam rau ADHD thiab txwv tsis pub haus luam yeeb. Nws yog noj ntawm qhov ncauj.
Protriptyline: Protriptyline , muag nyob rau hauv lub npe lag luam Vivactil ntawm lwm tus, yog tricyclic antidepressant (TCA), tshwj xeeb yog cov theem nrab amine, qhia txog kev kho mob ntawm kev nyuaj siab thiab saib xyuas qhov tsis txaus siab hyperactivity tsis meej (ADHD). Uniquely cov feem ntau ntawm cov TCAs, protriptyline nyhav yuav tsum tau energizing es tsis txhob ntawm sedating, thiab yog tej zaum kuj siv rau narcolepsy mus cuag ib tug wakefulness-txhawb cov nyhuv.
Doxepin: Doxepin yog cov tshuaj siv los kho kev mob siab, kev ntxhov siab, mob khaus, thiab muaj teeb meem tsaug zog. Rau qhov ua xua nws yog qhov kev xaiv tsawg dua rau tshuaj antihistamines. Nws muaj ib tug me ntsis kev pab rau pw tsaug zog teeb meem. Nws siv ua cov tshuaj loog rau khaus vim yog atopic dermatitis lossis lichen simplex chronicus.
Iprindole: Iprindole , muag nyob hauv cov npe lag luam Prondol , Galatur , thiab Tertran , yog cov tshuaj tiv thaiv kab mob tricyclic antidepressant (TCA) uas tau siv rau hauv tebchaws United Kingdom thiab Ireland rau kev kho mob kev nyuaj siab tab sis zoo li tsis muaj kev lag luam ntxiv lawm. Nws yog tsim los ntawm Wyeth thiab marketed nyob rau hauv 1967. Cov tshuaj twb tau piav los ntawm ib co raws li cov thawj "thib ob-tiam \" antidepressant yuav tsum tau ua tswvcuab. Txawm li cas los xij, nws tau siv tsawg dua li muab piv rau lwm tus TCA, uas muaj cov naj npawb ntawm cov tshuaj tau faib tawm tsuas yog ntau txhiab.
Melitracen: Melitracen yog tricyclic antidepressant (TCA), rau kev kho mob ntawm kev nyuaj siab thiab ntxhov siab. Nyob rau hauv tas li ntawd mus ib tshuaj preparations, nws tseem yog muaj raws li Deanxit, marketed los ntawm Lundbeck, thaum lawv tseem cov khoom uas muaj ob qho tib si melitracen thiab flupentixol.
Butriptyline: Butriptyline, muag nyob rau hauv lub hom lub npe Evadyne ntawm lwm tus neeg, yog ib tug tricyclic antidepressant (TCA) uas twb tau muab siv nyob rau hauv lub tebchaws United Kingdom thiab ob peb lwm yam European lub teb chaws rau cov kev kho mob ntawm kev nyuaj siab tab sis zoo nkaus li tsis muaj lawm yuav marketed. Nrog rau trimipramine, iprindole, thiab amoxapine, nws tau piav qhia raws li "atypical \" lossis \ "thib ob tiam \" TCA vim nws cov lus qhia pib qeeb thiab cov tshuaj muaj tshuaj atypical. Nws twb heev me ntsis-siv piv mus rau lwm cov TCAs, nrog rau cov xov tooj ntawm cov tshuaj dispensed xwb nyob rau hauv lub phav phav.
Dosulepin: Dosulepin , tseem hu ua beciepin thiab muag hauv qab hom npe Prothiaden ntawm lwm tus, yog tricyclic antidepressant (TCA) uas tau siv rau hauv kev kho mob ntawm kev nyuaj siab. Dosulepin yog ib zaug hauv lub feem ntau tus kws kho kev nyuaj siab nyob rau hauv lub tebchaws United Kingdom, tab sis nws yog tsis lug siv vim nws kuj muaj toxicity nyob rau hauv overdose tsis muaj tshuaj zoo tshaj lwm TCAs. Nws ua raws li ib tug serotonin-norepinephrine reuptake inhibitor (SNRI) thiab tseem muaj lwm yam kev ua ub no xws li antihistamine, antiadrenergic, antiserotonergic, anticholinergic, thiab sodium channel-thaiv cov hlab los.
Amoxapine: Amoxapine, muag nyob rau hauv lub hom lub npe Asendin ntawm lwm tus neeg, yog ib tug tetracyclic antidepressant (TeCA). Nws yog ib lub N-demethylated metabolite ntawm loxapine. Amoxapine thawj tau txais li kev pom zoo nyob rau hauv lub tebchaws United States nyob rau hauv 1992.
Dimetacrine: Dimetacrine , tseem hu ua dimethacrine thiab acripramine , yog tricyclic antidepressant (TCA) siv rau hauv Tebchaws Europe thiab yav dhau los hauv Nyij Pooj rau kev kho mob ntawm kev nyuaj siab. Nws muaj imipramine zoo li los; tab sis yog, nyob rau hauv ib tug muab ob npaug rau-dig muag soj ntsuam mus sib hais tiv thaiv imipramine, dimetacrine twb pom muaj tsawg miv nyuas siv zug nyob rau hauv kev sib piv thiab ua ntau yuag poob thiab txawv txav siab kev ntsuam xyuas. Me ntsis yog paub txog lub pharmacology ntawm dimetacrine, tab sis nws muaj peev xwm yuav inferred tias nws ua nyob rau hauv ib tug zoo li yam mus rau lwm cov TCAs. Yog tias qhov no yog qhov tseeb tiag, dimetacrine yuav ua rau mob lub plawv mob lom ntau heev nyob rau hauv kev noj haus dhau.
Amineptine: Amineptine, hu ua muag nyob rau hauv lub hom lub npe Survector ntawm lwm tus neeg, yog ib qho atypical antidepressant ntawm lub tricyclic antidepressant (TCA) tsev neeg. Nws ua raws li kev xaiv thiab sib xyaw dopamine reuptake inhibitor thiab tso tus neeg sawv cev, thiab rau tus neeg tsawg dua li tus norepinephrine reuptake inhibitor.
Maprotiline: Maprotiline, muag nyob rau hauv lub hom lub npe Ludiomil ntawm lwm tus neeg, yog ib tug tetracyclic antidepressant (TeCA) uas yog siv nyob rau hauv cov kev kho mob ntawm kev nyuaj siab. Nws tuaj yeem raug txiav txim siab tias yog cov tricyclic antidepressant (TCA), tshwj xeeb yog theem amine. Nyob rau hauv cov nqe lus ntawm nws cov chemistry thiab cov chaw muag tshuaj, maprotiline yog ze ze rau lwm cov theem nrab amine TCA zoo li nortriptyline thiab protriptyline, thiab muaj cov teebmeem zoo li rau lawv.
Quinupramine: Quinupramine yog tricyclic antidepressant (TCA) siv rau hauv Europe rau kev kho mob ntawm kev nyuaj siab.
ATC code N06: ATC code N06 Psychoanaleptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm alphanumeric code tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N06 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
Zimelidine: Zimelidine yog ib tus thawj xaiv serotonin reuptake inhibitor (SSRI) tshuaj tua kab mob los tiv thaiv kev lag luam. Nws yog pyridylallylamine, thiab tus yam ntxwv sib txawv ntawm lwm cov tshuaj tiv thaiv kev ntxhov siab.
Fluoxetine: Fluoxetine , muag nyob hauv cov npe lag luam Prozac thiab Sarafem ntawm lwm tus, yog cov tshuaj tiv thaiv kab mob ntawm cov tshuaj serotonin reuptake inhibitor (SSRI) hauv chav kawm. Nws yog siv rau kev kho mob ntawm kev tsis txaus siab loj, tsis txaus siab – compulsive tsis meej (OCD), bulimia nervosa, ceeb kev tsis meej, thiab premenstrual dysphoric tsis meej. Nws tseem raug pom zoo rau kev kho mob ntawm kev tsis txaus siab loj hauv cov hluas thiab menyuam yaus hnub nyoog 8 xyoo thiab tshaj saud. Nws kuj tau siv los kho kev ntxov ntxov. Fluoxetine yog noj ntawm qhov ncauj.
Citalopram: Citalopram , muag nyob rau hauv hom npe nrov Celexa ntawm lwm tus, yog tshuaj tiv thaiv kab mob ntawm cov kev xaiv serotonin reuptake inhibitor (SSRI) cov chav kawm. Nws yog siv los kho loj depressive tsis meej, obsessive compulsive tsis meej, ntshai tsis meej, thiab kev sib raug zoo phobia. Kev tiv thaiv kev ntxhov siab yuav siv li ib mus rau plaub asthiv los tshwm sim. Nws yog noj ntawm qhov ncauj.
Paroxetine: Paroxetine , muag nyob hauv cov lag luam muaj npe Paxil thiab Seroxat ntawm lwm tus, yog cov tshuaj tiv thaiv kab mob ntawm cov tshuaj serotonin reuptake inhibitor (SSRI). Nws yog siv los kho loj depressive tsis meej, obsessive compulsive tsis meej-, ceeb tsis meej, muaj kev ntxhov siab tsis meej, posttraumatic kev nyuaj siab tsis meej, generalized kev ntxhov siab vim teeb meem no thiab premenstrual dysphoric teeb meem. Nws tau kuj tau siv nyob rau hauv cov kev kho mob uas yug ntxov ejaculation thiab kub flashes vim lawm. Nws yog noj ntawm qhov ncauj.
Sertraline: Sertraline , muag nyob rau hauv hom npe Zoloft ntawm lwm tus, yog tshuaj tiv thaiv kab mob ntawm cov xim serotonin reuptake inhibitor (SSRI). Qhov ua tau ntawm sertraline rau kev nyuaj siab yog zoo ib yam li lwm cov tshuaj tiv thaiv kev nyuaj siab, thiab qhov sib txawv feem ntau tau cuam tshuam nrog cov kev mob tshwm sim. Sertraline yog zoo dua taus tshaj cov laus tricyclic antidepressants, thiab tej zaum nws yuav ua hauj lwm zoo dua fluoxetine rau ib co subtypes ntawm kev nyuaj siab. Sertraline yog zoo rau ceeb tsis meej, muaj kev ntxhov siab tsis meej, generalized kev ntxhov siab vim teeb meem, thiab obsessive-compulsive tsis meej (OCD). Txawm li cas los xij, rau OCD, kev paub txog kev coj cwj pwm, tshwj xeeb hauv kev sib xyaw nrog sertraline, yog kev kho mob zoo dua. Txawm hais tias pom zoo rau kev mob nrawm tom qab los, kev mob ntshav siab los ua rau muaj kev txhim kho me ntsis hauv tus mob no. Sertraline tseem daws qhov kev mob tshwm sim ntawm lub cev ua tsis taus pa thiab tsis tuaj yeem siv rau hauv kev txhaj tshuaj lossis sib quas ntus rau kev kho mob.
Alaproclate: Alaproclate yog ib qho tshuaj uas tau txhim kho cov tshuaj tiv thaiv kev npau taws los ntawm lub tuam txhab Swedish tshuaj Astra AB hauv xyoo 1970. Nws ua raws li kev xaiv serotonin reuptake inhibitor (SSRI), thiab nrog rau zimelidine thiab indalpine, yog ib tus ntawm thawj. Txoj kev loj hlob tau txiav vim tus soj ntawm daim siab mob nyob rau hauv nas cov kev tshawb fawb. Ntxiv rau nws cov yam ntxwv SSRI, alaproclate tau pom tias ua qhov tsis sib tw NMDA receptor antagonist, tab sis tsis muaj kev ntxub ntxaug cov khoom zoo ib yam li phencyclidine.
Fluvoxamine: Fluvoxamine , muag nyob rau hauv cov npe lag luam Luvox ntawm lwm tus, yog tshuaj tiv thaiv kab mob ntawm cov xim serotonin reuptake inhibitor (SSRI) cov chav kawm uas yog siv rau feem ntau kho mob kev nyuaj siab tsis meej thiab tsis xav xav tau – compulsive tsis meej (OCD). Nws kuj yog siv los kho kev ntxhov siab, xws li ceeb ntshai, kev txhawj xeeb ntawm kev sib raug zoo, thiab kev mob tom qab lub cev.
Etoperidone: Etoperidone , txuam nrog ntau hom npe tshuaj, yog cov tshuaj tiv thaiv atypical antantpressant uas tau tsim tawm xyoo 1970 thiab tog twg los tsis muaj muag lossis tsis muaj muag. Nws yog ib tug phenylpiperazine muaj feem xyuam rau trazodone thiab nefazodone nyob rau hauv tshuaj cov qauv thiab yog ib tug serotonin antagonist thiab reuptake inhibitor (Sari) piv rau lawv.
Escitalopram: Escitalopram, muag nyob rau hauv lub tshuaj uas nrov npe Cipralex thiab Lexapro, ntawm lwm tus neeg, yog ib qho kev nyuaj siab ntawm cov xim serotonin reuptake inhibitor (SSRI) hauv chav kawm ntawv. Escitalopram yog tsuas yog siv los kho loj depressive tsis meej los yog generalized kev ntxhov siab vim teeb meem. Nws yog noj ntawm qhov ncauj.
ATC code N06: ATC code N06 Psychoanaleptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm alphanumeric code tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N06 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
Isocarboxazid: Isocarboxazid yog ib tug uas tsis yog-xim, irreversible monoamine oxidase inhibitor (MAOI) ntawm lub hydrazine chav kawm ntawv siv raws li ib tug kev nyuaj siab. Nrog rau phenelzine thiab tranylcypromine, nws yog ib qho ntawm peb tsuas yog MAOI tseem muaj rau kev siv tshuaj kho mob hauv kev kho mob hlwb hauv Tebchaws Asmeskas, txawm hais tias nws tsis zoo li ua haujlwm hauv kev sib piv rau lwm tus.
Nialamide: Nialamide yog qhov tsis xaiv, xaiv tsis tau, monoamine oxidase inhibitor (MAOI) ntawm chav kawm hydrazine uas tau siv los ua tshuaj tiv thaiv kab mob. Nws tau raug tshem tawm los ntawm Pfizer ob peb lub xyoos dhau los vim muaj kev pheej hmoo ntawm hepatotoxicity.
Phenelzine: Phenelzine , muag nyob hauv hom tshuaj lag luam lub npe Nardil , ntawm lwm tus, yog qhov tsis xaiv thiab tsis muaj dab tsi monoamine oxidase inhibitor (MAOI) ntawm chav kawm hydrazine uas tau siv ua tshuaj tiv thaiv kev ntxhov siab thiab ntxhov siab. Nrog rau tranylcypromine thiab isocarboxazid, phenelzine yog ib qho ntawm MAOI uas tsis xaiv thiab tsis muaj kev cuam tshuam tseem nyob hauv kev siv kho mob. Nws yog noj ntawm qhov ncauj.
Tranylcypromine: Tranylcypromine yog monoamine oxidase inhibitor (MAOI); ntau yeej, tranylcypromine ua raws li nonselective thiab irreversible inhibitor ntawm lub enzyme monoamine oxidase (Mao). Nws siv raws li cov tshuaj tiv thaiv kev ntxhov siab thiab ntxhov siab ntawm kev kho mob hauv tsev kho mob ntawm lub siab ntsws thiab kev ntxhov siab tsis meej, feem.
Iproniazid: Iproniazid yog ib tug uas tsis yog-xim, irreversible monoamine oxidase inhibitor (MAOI) ntawm lub hydrazine chav kawm ntawv. Nws yog ib tug xenobiotic uas yog Ameslikas tsim los kho tus kab mob ntsws, tab sis yog tom qab feem ntau prominently siv raws li ib tug antidepressant tshuaj. Txawm li cas los xij, nws tau thim tawm los ntawm kev ua lag luam vim nws cov kab mob hepatotoxicity. Kev siv tshuaj kho mob ntawm iproniazid raug tso tseg nyob rau hauv feem ntau ntawm lub ntiaj teb hauv xyoo 1960, tab sis tseem siv nyob rau hauv Fabkis.
Iproclozide: Iproclozide yog ib qho tsis paub tseeb thiab xaiv monoamine oxidase inhibitor (MAOI) ntawm hydrazine tshuaj chav kawm uas tau siv los ua tshuaj tiv thaiv kab mob, tab sis txij li tau txiav tawm. Nws tau raug hu mus rau ua fulminant kab mob siab thiab muaj tsawg kawg yog peb qhia kuj tuag vim koom haum saib xyuas ntawm cov tshuaj.
ATC code N06: ATC code N06 Psychoanaleptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm alphanumeric code tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N06 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
Moclobemide: Moclobemide yog qhov thim rov qab los ntawm cov tshuaj monoamine oxidase A (RIMA) siv feem ntau los kho kev nyuaj siab thiab kev ntxhov siab hauv zej zog. Nws tsis pom zoo rau siv hauv Tebchaws Asmeskas, tab sis tau pom zoo nyob rau lwm lub tebchaws sab hnub poob xws li Canada, UK thiab Australia. Nws yog ua los ntawm affiliates ntawm lub Hoffmann-La Roche kws lub tuam txhab. Thaum pib, Aurorix tseem raug muag los ntawm Roche hauv South Africa, tab sis tau thim tawm tom qab nws txoj cai muaj cai tag sijhawm thiab Cipla Medpro's Depnil thiab Pharma Dynamic's Clorix los ua ib nrab ntawm tus nqi.
Toloxatone: Toloxatone (Humoryl) yog ib qho kev nyuaj siab launched nyob rau hauv 1984 nyob rau hauv Fabkis los ntawm Sanofi Aventis rau cov kev kho mob ntawm kev nyuaj siab. Nws twb txiav nyob rau hauv 2002. Nws ua raws li ib tug xim reversible inhibitor ntawm Mao-A (Rima).
ATC code N06: ATC code N06 Psychoanaleptics yog kev kho mob sib cais ntawm Anatomical Kev Ntsuas Cov Tshuaj Hauv Tshuaj, lub kaw lus ntawm alphanumeric code tsim los ntawm World Health Organization (WHO) rau kev faib tawm cov tshuaj thiab lwm cov khoom kho mob. Pawg N06 yog ib feem ntawm cov pab pawg anatomical N Cov kab mob tsis zoo .
5-Hydroxytryptophan: 5-Hydroxytryptophan ( 5-HTP ), tseem hu ua oxitriptan , yog ib txwm muaj cov amino acid thiab tshuaj ua ntej thiab ua rau cov tshuaj metabolic nrab nyob rau hauv biosynthesis ntawm neurotransmitter serotonin.
Tryptophan: Tryptophan yog ib qho α-amino acid uas yog siv nyob rau hauv lub biosynthesis ntawm proteins. Tryptophan muaj ib pawg α-amino, ib pawg α-carboxylic acid pab pawg, thiab rau sab hauv lub ntsej muag, ua rau nws tsis muaj cov kab mob uas muaj cov amino acid uas muaj ntxhiab tsw. Nws yog qhov tseem ceeb nyob rau hauv tib neeg, lub ntsiab lus hais tias lub cev tsis tau ke nws thiab nws yuav tsum muab tau los ntawm cov khoom noj. Tryptophan kuj yog ib tug precursor rau lub neurotransmitter serotonin, lub hormone melatonin, thiab vitamin B3. Nws yog kho los ntawm cov codon UGG.
Mianserin: Mianserin , muag nyob hauv hom tshuaj npe Tolvon ntawm lwm tus, yog tshuaj tua kab mob atypical uas yog siv feem ntau kho kev nyuaj siab ntawm Tebchaws Europe thiab lwm qhov hauv lub ntiaj teb. Nws yog ib tug tetracyclic antidepressant (TeCA). Mianserin muaj feem xyuam zoo rau mirtazapine, ob qho tib si hauv tshuaj thiab ntawm nws cov kev coj ua thiab cuam tshuam, txawm hais tias muaj qhov sib txawv tseem ceeb ntawm ob lub tshuaj.
Nomifensine: Nomifensine yog ib qho norepinephrine-dopamine reuptake inhibitor, piv txwv li ib cov tshuaj uas tsub kom tau txais txiaj ntsig synaptic norepinephrine thiab dopamine muaj rau cov neeg txais khoom los ntawm thaiv cov dopamine thiab norepinephrine reuptake thauj cov neeg thauj khoom. Qhov no yog ib tug mechanism ntawm qhov kev txiav txim qhia los ntawm ib co tshuaj ua si zoo li yeeb thiab cov tshuaj tametraline. Kev tshawb fawb pom tias cov (S) -isomer yog lub luag hauj lwm rau kev ua si.